CONSERVATIVE TREATMENT OF NEUROTROPHIC KERATITIS
نویسندگان
چکیده
منابع مشابه
[Neurotrophic keratitis].
Neurotrophic keratitis is a degenerative disease of the cornea caused by reduced corneal innervation. Trauma, tumors, inflammatory lesions and surgical procedures can damage the first branch of the trigeminal nerve on its entire course from brainstem to and within the cornea. Loss or reduction of corneal innervation leads to a reduced aqueous phase of the tear film and due to reduced supply wit...
متن کاملNeurotrophic Keratitis
Neurotrophic keratitis (NK) is a rare degenerative corneal disease that occurs as a result of partial or total impairment of trigeminal innervations, leading to a reduction (hypoesthesia) in or loss (anaesthesia) of corneal sensitivity. The impairment of sensory innervation causes a reduction in the lacrimation reflex and the vitality, metabolism and mitosis of epithelial cells, with subsequent...
متن کاملDiagnosis and management of neurotrophic keratitis
Neurotrophic keratitis (NK) is a degenerative disease characterized by corneal sensitivity reduction, spontaneous epithelium breakdown, and impairment of corneal healing. Several causes of NK, including herpetic keratitis, diabetes, and ophthalmic and neurosurgical procedures, share the common mechanism of trigeminal damage. Diagnosis of NK requires accurate investigation of clinical ocular and...
متن کاملSemaphorin 7a in Herpetic Neurotrophic Keratitis.
Recurrent infection of the ocular surface by herpes simplex virus type I (HSV-1), a neurotropic herpesvirus, is a leading infectious cause of corneal blindness in developed countries. The origin of recurrent infections lies in the fact that the virus establishes latency in sensory neurons of the trigeminal ganglion (TG). While the latent infection of TG is marked by the loss of viral protein sy...
متن کاملApplication of umbilical cord serum eyedrops for the treatment of neurotrophic keratitis.
PURPOSE To investigate the efficacy of umbilical cord serum eyedrops for the treatment of neurotrophic keratitis. DESIGN Prospective noncomparative case series. PARTICIPANTS Twenty-eight eyes of 28 patients with neurotrophic keratitis who were refractory to conventional treatment. METHODS The patients with neurotrophic keraitis were treated with 20% umbilical cord serum eyedrops 6 to 10 t...
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ژورنال
عنوان ژورنال: Medical Council
سال: 2017
ISSN: 2079-701X
DOI: 10.21518/2079-701x-2017-5-162-166